Hello everyone :
Here is some news about the metabolic mechanisms related to time restricted eating, also called intermittent fasting, can lead to better fat metabolism.
“Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity… Circadian control of adipocyte creatine metabolism underlies the timing of diet-induced thermogenesis, and enhancement of adipocyte circadian rhythms through overexpression of the clock activator brain and muscle Arnt-like protein-1 (BMAL1) ameliorated metabolic complications during diet-induced obesity. These findings uncover rhythmic creatine-mediated thermogenesis as an essential mechanism that drives metabolic benefits during time-restricted feeding.”
“Such thermogenesis (fat burning) depended on the circadian clock of adipocytes and on increased synthesis of creatine, fueling a futile cycle of ATP turnover in the mitochondria of adipocytes. These results help to explain the benefits of time-restricted feeding and how circadian disruption can contribute to metabolic disease.”
https://www.science.org/doi/10.1126/science.abl8007
Bottom Line:
To summarize this paper, eating outside of the natural circadian rhythms leads to weight gain, and eating according to the inborn circadian rhythms by utilizing time-restricted feeding lowers your risk for metabolic disease…such as all cardiovascular diseases, cancer, diabetes, dementia, and all inflammatory based diseases and disorders.
What is the natural circadian rhythm for eating? It appears that the old phrase is right-on: eat breakfast like a king/queen, lunch like a prince/princess and dinner like a pauper…and getting all your calories within a 10-hour window is optimal. Not only that, this type of eating can lower your inflammation even more than just eating an anti-inflammatory food plan by itself.
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