Health Update: Time Restricted Eating Lowers Fat Gain

RVAchironeuro • March 20, 2023

Hello everyone :

Here is some news about the metabolic mechanisms related to time restricted eating, also called intermittent fasting, can lead to better fat metabolism.

Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity … Circadian control of adipocyte creatine metabolism underlies the timing of diet-induced thermogenesis, and enhancement of adipocyte circadian rhythms through overexpression of the clock activator brain and muscle Arnt-like protein-1 (BMAL1) ameliorated metabolic complications during diet-induced obesity.  These findings uncover rhythmic creatine-mediated thermogenesis as an essential mechanism that drives metabolic benefits during time-restricted feeding.”

 “Such thermogenesis (fat burning) depended  on the circadian clock of adipocytes  and on increased synthesis of creatine, fueling a futile cycle of ATP turnover in the mitochondria of adipocytes.  These results help to explain the benefits of time-restricted feeding and how circadian disruption can contribute to metabolic disease .”

Bottom Line:

To summarize this paper, eating outside of the natural circadian rhythms leads to weight gain, and eating according to the inborn circadian rhythms by utilizing time-restricted feeding lowers your risk for metabolic disease…such as all cardiovascular diseases, cancer, diabetes, dementia, and all inflammatory based diseases and disorders.

What is the natural circadian rhythm for eating? It appears that the old phrase is right-on: eat breakfast like a king/queen, lunch like a prince/princess and dinner like a pauper…and getting all your calories within a 10-hour window is optimal. Not only that, this type of eating can lower your inflammation even more than just eating an anti-inflammatory food plan by itself.

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Health News Update: Pesticides, Cancer & Why Go Organic 6.29.26 Hello everyone: Slowly but surely, despite the health and food industries downplaying the risks, evidence is emerging that the long-term consumption of trace amounts of toxic chemicals can add up to some serious health consequences. “Our process-based model, encompassing 31 key pesticide active ingredients, together with an innovative stratification of cancer cases by developmental lineage, reveals a robust spatial association between environmental pesticide exposure risk and cancer incidence. In pesticide-associated cancer hotspots, exposomic profiling of liver tissue—a primary target of chemical carcinogens—uncovers a distinct transcriptomic signature of pesticide exposure, implicating a non-genotoxic mode of action that disrupts core regulatory circuitries sustaining cell identity. Collectively, these findings strongly support a mechanistic link between pesticide exposure and cancer, challenging assumptions of human non-carcinogenicity derived from reductionist experimental models. This study redefines the exposome as a lineage-conditioned, mechanistically tractable framework and shows how complex pesticide mixtures can contribute to carcinogenic trajectories, with profound and far-reaching implications for global health policy and socio-ecological equity.” https://www.nature.com/articles/s44360-026-00087-0 pesticide exposure & cancer risks Bottom Line: Whenever possible, purchase your food from organic sources including local farmers that use regenerative and organic practices. Not all foods need to be organic, and to decide which ones absolutely need to be, you can access the Environmental Working Group’s yearly list of the Dirty Dozen foods that are the highest in pesticide residues. This will also include the Clean 15 foods that do not need to be organic as they are usually grown without or with very low pesticide levels. https://www.ewg.org/foodnews/dirty-dozen.php dirty dozen food guide Additionally, high quality nutrients support the natural detox processes our bodies use to get rid of any and all toxins. When we consume the Standard American Diet or Westernized Diet, we are low in the nutrients and co-factors needed to support optimal detox cleansing. So always start with food upgrades as they will carry your upgrade the farthest. Remember that most chronic health conditions start 20 years before you even notice them creeping up or becoming diagnosed. What you do now is creating your future. It used to be said that you are what you eat. Another way to say that is we become what we eat…so please take good care and make sure you always put high grade fuel into your Temple.
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