Covid-19 Update: What’s in The Pfizer Vaccine That Just Won FDA Approval?

RVAchironeuro • December 14, 2020

Hello again everyone:

  I get this question a lot, and one reason is that there is a lot of vaccine hesitancy due to the lack of transparency about the vaccine trials, how effective they are, and how safe they will be. We have had press releases, but not the actual data yet, and most experts feel that while the vaccine is ‘safe’, the true rate and various types of possible adverse reactions will not be known until it has been widely used, and this is true for virtually all vaccines and prescription medicines. For this reason and others, there is a lot of hesitancy even in the medical field, so for a proper perspective, this entire article is worth the quick read:

“We are vaccines’ greatest champions, but this is the first time that a new vaccine has been developed at a rapid pace in the middle of a pandemic, as opposed to a much longer timeline,” Susan Bailey, a physician in Fort Worth and president of the American Medical Association, said in an interview. “What I hear from physicians is some of the same concerns that are expressed by everyone. They worry the process has been politicized. They are concerned because they haven’t seen any published data yet. And they don’t feel comfortable making the decision one way or another until they see the evidence,” Bailey said.

So, here is some of that evidence in the form of great information about what is actually in the vaccine, and this may help alleviate fears a bit until we get more data from Pfizer. This article is pretty short and easy to read and understand so please give it a few minutes as it is worth it:

Bottom Line:
While I consider myself to be vaccine hesitant, from my studies and speaking with other clinicians, the hard truth emerges that vaccination of a large portion of the population may be essential to slow down and finally end this pandemic. I may not like that, but that is the way it is. One reason for this is that the U.S. is the most co-morbid country in the world, the data on this I have discussed in a previous blog and this is likely why we have been hit so very hard by this virus.

However, part of the hard truth is that vaccines are not risk free, so making the decision to take the vaccine requires knowledge of the risk versus benefit profile. Right now, the death rate is around 2% of those infected and around 10 to 50% of those will have long term complications currently categorized as Long Hauler’s or Post Covid syndrome. With 2000 to 3000 deaths per day in the U.S., and many survivors developing chronic illness and disabilities, the risk/benefit ratio leans towards vaccination of the most vulnerable as part of the overall strategy along with other public and private health measures.

This entire pandemic has a lot of moving parts that can create an atmosphere that is foggy and hard to see through clearly. It is tempting for all sides on these arguments to tend to over-simplify the issues to create emotional responses, and yes, all of this information and misinformation is very worrying and helps to create hesitancy and a sense of mistrust…and this is what has happened. It is my sincere hope that the good and well-intentioned people involved in these vaccine trials will step up and release the data, and I believe they will, so keep an eye out for this information. This information will allow each one of us to make the best decision we can, and it may not be an easy decision to make…I know that I don’t like that either, and that is just the way it is. These are really unusually tough and challenging times and getting informed will allow us to step up and make a decision.

Thus, in actuality we would all be served better if this was kept to a scientific dialogue which usually allows the truth to emerge and the best results to be obtained. Please refer to my earlier blog about what to expect when the vaccine is actually rolled out (see link below). The experts are telling us that masking along with distancing will be required for many more months, even with an effective vaccine. This is truly important, and you should read it and keep expectations rooted in reality:

We are certainly all in this together, and even though we may not want to, we need to face up to this situation and get realistic about this, …we all need to find that inner strength to rise up to this crisis and find ways to do whatever is needed to keep each other well and safe. This applies to yourself as well. Consider that the evidence is clear: it may not be a good idea to put all of your eggs in one basket…that is, waiting for the vaccine may not be your best single strategy… and this simply means that it is still extremely important to become as metabolically healthy as possible to reduce your risk of infection as well as possibly lowering the severity and duration. Additionally, these efforts will probably make any vaccine you take more likely to be effective with a lower risk overall. It is totally worth your while to reduce your comorbidities (if you have any) by eating right, moving right, de-stressing, getting proper sleep, avoiding sugar and processed foods, try to keep a prayerful attitude (this helps me the most), taking your supplements, maintain proper masking/social distancing advice, prop up and strengthen your resilience and find ways to be of service to others.

We simply need to use all of the tools in the toolbox…from vaccines to vitamins…so now is the time to seriously upgrade your health as we can use this pandemic as an opportunity to jump start our return to optimal form, both as individuals and as a country and as a planet. 

Keep Calm…and Get Healthy! 

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To Avoid Chronic Disease, Watch What You Eat
By Mark Smith August 25, 2025
Hello everyone: I think I have mentioned inflammaging before but never really focused on it. So, let’s dig into this interesting topic. Inflammaging is when chronic, low-grade inflammation develops with age as dietary and environmental stress accumulates, contributing to the development of all of the various age-related diseases and health issues. It results from a loss of control over systemic inflammation, which tends to come from an unbalanced and dysregulated immune system. One of the key drivers of inflammaging is diet…which means that one of the key tools to slow and reduce aging is our what we eat as well as what we don’t eat. In this paper, the authors reveal that the typical Western Diet (what science calls the Standard American Diet or S.A.D.) is the best example of a pro-inflammatory diet pattern. “ Conclusion: Inflammation is a key physiological process in immunity and tissue repair. However, during aging it becomes increasingly more chronic. In addition, we found that certain foods such as saturated fats have pro-inflammatory activity. Taking this into account, in this review we have proposed some dietary guidelines as well as a list of compounds present in foods with anti-inflammatory activity. It must be taken into account that the amounts used in the studies that detect anti-inflammatory activity of these compounds are very high, and the intake of a single food to achieve its anti-inflammatory power is not feasible. (My Comment: what this means is that it is the overall dietary pattern that matters the most.) However, the combination of foods rich in compounds with anti-inflammatory activity could exert beneficial effects during aging and in pathologies associated with inflammation and in reducing the detrimental effects of foods with pro-inflammatory activity. Therefore, we can conclude that the compounds in our diet with anti-inflammatory activity could help alleviate the inflammatory processes derived from diseases and unhealthy diets and thereby promote healthy aging. Thus, we can use diet not only for nourishment, but also as medicine.” https://pmc.ncbi.nlm.nih.gov/articles/PMC8389628/ anti-inflammatory diet and health aging https://www.healthline.com/health/5-minute-guide-to-inflamm-aging Bottom Line: We all must age, and how we do so is largely under our own control. To create an anti-inflammatory lifestyle is not that difficult, especially if you put it all together in stages. Start with a clean, whole-food, unprocessed plant-based food plan. And to begin, first focus on what you can add into your menus and use those additions to sort of crowd out the things that are more inflammatory…sugar, refined grains, processed and pre-packaged things. Set realistic goals such as going plant based one or two days a week, or even one meal…just start and gradually work up. It has to be doable so don’t stress. Next, start moving and doing regular exercise at least three times a week…and find what you enjoy doing and focus on that. Then add activities that de-stress you, whether that is socializing, church, meditation, prayer, yoga, etc. Overall, shift your attention to giving love to things that love you back. Sugar, drive-thru and processed food like thingies do not love you back but apples or kiwis or berries or veggies do. Sitting around does not love you back but going for a short walk after a meal does love you back. Hang out and give love to the people you really like to be with, they will most always love you back. Create a love you back lifestyle and see how you feel.
By Mark Smith August 18, 2025
Hello everyone: I frequently hear about mental health issues with the people in our practice. They could be experiencing depression, or anxiety, feel flat, can’t focus or sustain attention, or may not feel well in general. These comments can come from anyone of any age…I can hear from parents about their kids, or it may be themselves experiencing these feeling. So, when I read this paper, it felt important to share it because we all seem to have mobile phones. Here is how the paper is summarized: “Concern about how smartphones affect users is widespread: half of American smartphone users—and 80% of those under age 30—worry that they use their device too much, and correlational research suggests that smartphone use is negatively related to mental health and cognitive functioning. However, few large-scale experiments have tested for causal effects. We report such an experiment, finding that blocking mobile internet for 2 weeks reduces smartphone use and improves subjective well-being (SWB) (including life satisfaction and positive affect), mental health (more than antidepressants), and sustained attention (as much as being 10 years younger). Despite the many benefits mobile internet offers, reducing the constant connection to the digital world can have large positive effects.” https://academic.oup.com/pnasnexus/article/4/2/pgaf017/8016017?utm_source=klaviyo&utm_medium=email&utm_campaign=%28Email%20-%20Chris%20Kresser%20General%20News%29%20Chris%27s%20Friday%20Favorites&utm_term=randomized%20controlled%20trial&utm_content=randomized%20controlled%20trial&_kx=fARhTo_gi8X3B_2-MaeO_RyzUl9tvT3tr4re-Dy7cNQ.my75y6 Bottom Line: It seems like a smartphone ‘timeout’ can be very beneficial for mental, emotional, physical health and can be an important part of stress reduction. The world today, with nearly instant communications, the almost constant bad and anxiety promoting news, and the fast pace of data consumption can add up to significantly stress us out and pull us down…or just simple keep us distracted. From what I can see, a ‘timeout’ may be just what the doctor ordered.
By Mark Smith August 11, 2025
Hey there everyone: As you know, inflammation causes, perpetuates, and/or aggravates every known human condition, including aging. As we age, we become more vulnerable to non-communicable diseases such as heart attack, stroke, high blood pressure, cancer, diabetes, dementia, arthritis and more. How we eat can massively reduce our inflammatory burden and promote health as we age. It is your choice. One reason that I keep writing on this is that I keep running into the mindset that these diseases are inevitable and that there is nothing we can do about it. Plus, because there are so many different diets for sale out there, it becomes hard to know what to eat. What is important for you to know is that there is a growing scientific consensus about what to eat, but the media rarely mention it and our public health authorities don’t either. It definitely seems like money is more important than our health. So…consuming an overall low-inflammatory diet is what the science is adding up to show it is the healthiest way to go, plus it actually gives you power over your future. This is a great article worth the time it takes to read it as it is pretty comprehensive. Bottom Line: “To adopt an anti-inflammatory dietary pattern, it is recommended to replace refined grains with whole grains, substitute healthy fats (such as nuts, seeds and fatty fish) for saturated and trans fats and increase the consumption of colorful fruits and vegetables while reducing the intake of sugary and processed foods. Additionally, choosing lean protein sources like fish and legumes over red and processed meats, using herbs and spices (such as turmeric, ginger, garlic and cinnamon) in place of excessive salt and sugar and consuming probiotic-rich foods (such as yogurt and kefir) instead of processed and sugary snacks are advised. These dietary adjustments can help mitigate inflammation and promote overall health.” https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/overview-of-antiinflammatory-diets-and-their-promising-effects-on-noncommunicable-diseases/AA3166846841DCC1B219C063F52E2A7F (anti-inflammatory diet)
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